Applied Food Sciences (AFS) announced the launch of MycoThrive™ Lion's Mane, a functional ingredient recently clinically studied to enhance cognitive performance and emotional well-being. This launch marks an advancement in the natural supplements industry for those seeking functional mushrooms that may boost their mental acuity and mood.

In a double-blind, randomized, placebo-controlled crossover study, 40 healthy adults were evaluated to determine the acute (single-dose) effects of 1000 mg of lion's mane mushroom extract on cognitive performance and mood. The study introduces MycoThrive™ Lion's Mane (previously known as "Nordic Lion's Mane") as a potent new addition to AFS' innovative lineup of functional ingredients.

Lion's Mane (Hericium Erinaceus) is renowned for its cognitive-enhancing properties and long history of use in Eastern medicine. Known as the "Mountain Priest" or "Smart Mushroom," its bioactive compounds, including β-glucan polysaccharides, proteins, hericenones, and erinacines, all play a role in how the ingredient functions in the human body.


"AFS takes pride in offering scientifically validated, high-quality ingredients. After extensive research on the science of fungi, we developed a love for mushroom ingredients and took on the challenges of creating consistent mushroom extracts standardized to their active compounds. Although the mushroom category is growing in the US, much still needs to be discovered about the scientific and quality aspects. Therefore, we are thrilled to enter this space with significant investment by offering our innovative line of MycoThrive™ mushroom ingredients and conducting the clinical studies needed to bring more validation to the market." -- Loretta Zapp, CEO, Applied Food Sciences


The study examined the effects of a single dose of 1000 mg of MycoThrive™ Lion's Mane extract next to a 650mg dose of guayusa extract (AmaTea® Max) and a placebo. Participants were tested at baseline, 60 minutes, and 120 minutes post-ingestion using comprehensive neuropsychological assessments like the Go/No-Go, Serial-Sevens, and N-Back tasks, as well as subjective measures for cognitive perception and mood.

Participants taking MycoThrive™ Lion's Mane demonstrated acute improvements in working memory, attention, concentration, and reaction time, with results noticed in as little as one-hour post-ingestion. The results were statistically significant compared to the placebo. Additionally, participants taking MycoThrive™ Lion's Mane recorded enhancements in mood scores such as "feelings of happiness," reflecting that the ingredient had a significant impact on their emotional well-being. 

This study is pivotal in understanding the acute, single-dose response of lion's mane in healthy adults. The results contrast the prevailing notion that Lion's Mane only produces chronic benefits after 30-60 days of use. While chronic use is still advantageous, this research provides valuable insights that help reinforce the credibility of MycoThrive™ Lion's Mane as a more immediate-acting nootropic for manufacturers to use in their cognitive-enhancing products. Moreover, it helps address the pressing need for transparency by providing more consistent structure-function claims, reducing skepticism, and increasing confidence in the market.

www.appliedfoods.com